Caffeine
Topical Caffeine to stimulate scalp and beard hair growth.
A natural stimulant commonly found in coffee, tea and various plants, caffeine is also a promising ingredient for stimulating hair to regrow. Caffeine works through a number of actions to boost the growth, length and thickness of hairs. Topical caffeine is an increasingly popular ingredient in anti hair loss treatments.
Benefits in Hair Loss
There is scientific evidence suggesting that caffeine can act as an anti hair loss ingredient by targeting several mechanisms. One key effect of caffeine is its ability to prolong the active growth phase of hair follicles. This can result in denser hair growth. There is also evidence that caffeine protect against the negative effects of dihydrotestosterone (DHT) which is a hormone closely linked to androgenetic hair loss. As such it can help maintain hair follicle health and density. Beyond this, caffeine may also improve blood circulation to the scalp which means increasing nutrient delivery and growth factors to the follicles hence allowing healthier and thicker hair regrowth. As such the main benefits of using topical caffeine in hair growth treatments include:
- Stimulates Hair Growth
- Slows Androgenetic Hair Loss
- Improves Hair Density
- Boosts Hair Health
- Can be Combined with Other Ingredients to Enhance Their Effects

Treatments with Topical Caffeine
At City Skin Clinic we use topical caffeine in our personalised anti hair loss and beard growth treatments depending on the patient’s needs. We commonly add caffeine to the following custom formulations to help regrow hair:
Complimentary Actives
We usually combine topical caffeine with other medicines or compounds to enhance their effects. This is because it depends on type of hair loss and individual patient circumstances or needs. The most common ingredients we use alongside caffeine include:
- Tretinoin: may enhance the absorption of other hair growth ingredients and improve their effectiveness.
- Minoxidil: promotes hair regrowth and improve hair density.
- Spironolactone: can help reduce androgen levels and treat hair loss in some cases of pattern hair loss.
- Hydrocortisone: may reduce scalp irritation caused by actives like Minoxidil and/or Tretinoin.
- Finasteride: reduces hair loss and promote regrowth by inhibiting the actions of DHT.
- Dutasteride: this also inhibits DHT to enhance hair regrowth.
- Biotin: may strengthen hair by supporting keratin production.
- Melatonin: regulates hair growth and protects follicles from oxidative stress. This can help increase hair density and length.
Topical Caffeine Hair Loss Treatments in the UK
In the UK, topical caffeine is available in over-the-counter products like shampoos and serums which aim to regrow hair. It is also available in compounded prescription treatments where it may be formulated with medicines like Minoxidil, Finasteride, Dutasteride or Spironolactone. We personalise our hair loss and beard growth serums based on what is appropriate and safe for each patient. The concentrations and ingredients we use depend on each individual patient’s hair loss, medical history and treatment goals.
To access our custom hair growth treatments, you will need to complete an online consultation form or book a virtual video consultation with one of our doctors first. They will then design the best and safest treatment for you. Your doctor will also take into account any wishes or preferences you have wherever possible. They will provide you with ongoing support and monitoring throughout your journey. You will be able to connect with your doctor by email at any time during your treatment.
TREATMENT FEES (UK BASED PATIENTS ONLY)
VIRTUAL CONSULTATION£30
Your doctor will design a personalised treatment and program for you to follow. The cost of the consultation will be deducted from any treatment purchase.
PERSONALISED HAIR LOSS TREATMENT£120
This is a 3 month supply of hair loss treatment (100ml). Your doctor will create a personalised treatment taking into account your health, hair loss concerns, goals and wishes.
PERSONALISED BEARD GROWTH TREATMENT£120
This is a 3 month supply of beard growth serum (100ml). Your doctor will create a personalised treatment to meet your beard growth needs.
Treatment Time
15 Minutes
Duration of effect
3-4 Months
Back to Work
Same Day

Important Information
Topical caffeine is an effective and generally safe anti hair loss ingredient when used as directed. However, you should still be aware of potential side effects and contraindications.
Safety and Side Effects
Although topical caffeine formulations usually have minimal side effects, some individuals may experience mild scalp irritation, itching or dryness upon initial use. These symptoms typically resolve quickly. If severe irritation or allergic reactions occur, discontinue use immediately and seek medical help.
Contraindications
Certain situations may require extra caution or avoidance when using topical caffeine products. These include:
- Scalp Conditions: Individuals with scalp disorders such as psoriasis, severe dermatitis or open wounds should consult with a healthcare provider before using topical caffeine treatments.
- Pregnancy and Breastfeeding: The safety of topical caffeine during pregnancy or breastfeeding has not been conclusively established. Consult with your medical provider prior to use in these circumstances.
- Allergies: Avoid caffeine-based products if you have known allergies or hypersensitivity to caffeine or any other ingredients in the product.
Storage and Shelf Life
Store caffeine-based hair products in a cool, dry place, away from direct sunlight and heat to maintain product effectiveness. Discard any medication that has changed in appearance or smell.