Hyperpigmentation Treatment

Fade dark spots and Even Out Skin Tone with Personalised Hyperpigmentation Skincare

We provide personalised treatment for uneven skin pigmentation and hyperpigmentation through our online skin clinic. Our doctors use science-backed ingredients where appropriate to design a hyperpigmentation cream or gel centred around your specific skin concerns and goals to fade dark spots and patched for brighter and more even skin. Your doctor will then take care of you through out your journey. Even better, you can access our hyperpigmentation treatment services from the comfort of your home through our online skin clinic.

Understanding Hyperpigmentation

Hyperpigmentation is a common usually harmless condition that can affect all skin types. It can also affect any part of the body including the face, hands, back and neck. Usually hyperpigmentation occurs when the skin produces an excess amount of melanin (the pigment that gives skin its colour). This can lead to patches of skin that appear darker than the rest giving an uneven complexion overall. The main causes of hyperpigmentation include sun exposure, hormonal changes, inflammation, age and genetics. As such, the main types of hyperpigmentation are:

We feel that understanding the types and causes of hyperpigmentation is a pivotal step towards effective skin pigmentation treatment.

Why Personalisation Matters

The variety of causes of hyperpigmentation and the different impact they have on different skin types and tones makes it hard to take a one-size-fits all approach. For this reason we believe the best way to treat hyperpigmentation is with a personalised approach which addresses the specific causes and unique characteristics of your skin. Your doctor will assess your skin and medical history in detail to understand the underlying causes of your hyperpigmentation. They will then design a treatment using the ingredients that will be most effective for your specific concerns and goals.

Personalised Prescription Strength Hyperpigmentation Treatments

We’re extremely proud to offer safe and effective personalised hyperpigmentation treatment through our online clinic. Your doctor will design your treatment based on your skin condition, medical history and goals. They will also take into account any wishes or concerns you have as much as possible when designing your acne treatment cream or gel. We offer two types of skin pigmentation treatment protocols – HYPR and HYPR+. Both of these are custom made treatments but have some differences:

  • HYPR: This is our standard treatment protocol which targets mild to moderate hyperpigmentation, scars and texture. It is also the treatment we use for maintenance once your skin clears up. HYPR comes as a single product which you use at night as directed by your doctor.
  • HYPR+: This is our advanced treatment protocol for severe hyperpigmentation. HYPR+ is designed for use for no more than 6 months and then you would continue with HYPR for maintenance and general skin improvement. This treatment contains two products (a morning and night treatment).

Ingredients in Our Hyperpigmentation Treatments

We design a personalised hyperpigmentation treatment for each and every single one of our patients using ingredients based on your unique skin concerns, goals and wishes (as much as possible). This is not a static treatment either. The components of your cream or gel may change at the end of each 3 month course of treatment based on your skin’s response. These are some of the active and prescription ingredients we may use in our topical pigmentation treatment creams or gels:

  • Tretinoin: this is a medication that we may use either alone or with other ingredients in your hyperpigmentation cream or gel. It works by promoting skin cell turnover, which helps smooth texture and fade mild hyperpigmentation. Tretinoin is up to 20x more powerful than retinol so it is a prescription only medicine and needs careful monitoring.
  • Azelaic Acid: has antibacterial, anti-inflammatory and keratolytic properties. It can help fade uneven pigmentation and promote smoother skin.
  • Niacinamide: reduces redness and inflammation, evens out skin tone and enhances the skin barrier.
  • Hydrocortisone: is a corticosteroid that reduces inflammation and soothes irritated skin. We sometimes add it in to manage certain types of hyperpigmentation.
  • Arbutin: this is a natural skin-brightening agent that reduces melanin production and is particularly effective in lighter skin tones.
  • Hydroquinone: is another prescription active which inhibits melanin production that we may use for limited periods in hyperpigmentation medication for suitable patients.

Please note that we only use prescription medications for hyperpigmentation treatment if we deem them safe, appropriate and acceptable for the patient.

Regain Confidence with Personalised Hyperpigmentation Treatments

Whilst hyperpigmentation can be difficult to shift, our tailored approach can help find the best treatment for you. We leverage the power of active and prescription ingredients where appropriate in our hyperpigmentation treatment to even out your complexion and give you smoother brighter skin. Whether you require our once daily HYPR or twice-daily HYPR+ protocol, your doctor will ensure that your treatment is always based around your skin condition, health, goals and preferences.

Hyperpigmentation Treatment at City Skin Clinic

We are devoted to providing personalised and effective hyperpigmentation treatments that are customised to your individual skin problems. Our approach to skincare combines personalised skincare protocols and powerful prescription strength ingredients to combat dark spots, rough texture and hyperpigmentation.

Hyperpigmentation Treatment Fees (3 Month Supply)


    Our expert doctor will design a personalised treatment for you and provide ongoing support. The cost of the consultation will be deducted from your first treatment.

  • HYPR£90

    Standard treatment (30g) for mild to moderate hyperpigmentation. Used nightly.

  • HYPR+£150

    This is an advanced treatment severe hyperpigmentation. It comes as two products (day and night treatment). HYPR+ is typically used for no more than 6 months consecutively. Each bottle contains 30g of treatment.

Treatment Time Clock

Treatment Time
15 Minutes

Duration of effect calendar

Duration of effect
3-4 Months

Back to work briefcase

Back to Work
Same Day

Start Your Online Consultation

The journey to great skin starts here. Start your online consultation for personalised prescription-strength skincare.

Start Consultation
Steps for online dermatology prescription skin clinic UK

Why Choose City Skin Clinic

Video or Form Consultations: We take customisation seriously and your journey starts with choice of either a detailed form consultation or in-depth video consultation with one of our aesthetic doctors. Which one you choose is totally up to you and your availability or preferences. Regardless of which consultation type you choose, you will always get a personalised treatment. Your doctor will review your concerns, evaluate your skin and develop a treatment plan that’s unique to you.

Comprehensive Aftercare: Your skincare journey doesn’t end after your virtual consultation. You will be able to directly contact your doctor at any point for further advice, progress monitoring and refills.

Convenience: Our online hyperpigmentation treatment clinic offers you high quality care and monitoring. All from the comfort of your own home. All treatments are delivered straight to your home.

From the initial consultation to follow-up, our team is with you every step of the way. Your doctor will provide expert advice, tailored treatments and support.

Personalised skincare that actually works and why you should use city skin clinic online skincare dermatology clinic

Start Your Online Consultation

The journey to great skin starts here. Start your online consultation for personalised prescription-strength skincare.

Start Consultation

Frequently asked questions

No it is not. We are really passionate about putting you in control of your treatment. Everyone responds differently and we may adjust your treatment formula after completing each course based on how your skin responds. That's why we don't think subscriptions make sense for a personalised journey. We leave it up to you to let us know when you need a refill and we make it very easy to order these.

We encourage all our patients to express any preferences they have in terms of treatment during the consultation. Wherever possible we will respect and accommodate these as long as we feel it is medically safe and beneficial to do so. Ultimately our aim is to provide you with the best solution for your concern and we'll design your treatment to achieve that.

This depends on how frequently you use it and how much you use. In general if used as instructed then the treatment should last 3 months for use on the face and neck. Please note that compounded treatments always have an expiry date of 3 months.

The duration can vary depending on the severity of the hyperpigmentation and the products used. Generally, early noticeable results are may be seen within 8 to 12 weeks of consistent use.

Most of our products are designed to be gentle on the skin. However, as some treatments can cause initial dryness, irritation or peeling, we recommend discussing any skin sensitivities with our doctor so we can adjust your treatment plan accordingly.

Hyperpigmentation can return if the skin is exposed to the same conditions that caused it initially, such as sun exposure or hormonal changes. To maintain your results, it's important to continue protecting your skin, even after your hyperpigmentation has improved. We also recommend using HYPR regularly to build on and maintain your results.

Most of our prescription hyperpigmentation treatments are not recommended for use during pregnancy or breastfeeding. Please inform our team if you are pregnant, planning to become pregnant, or breastfeeding so we can provide safe and suitable treatment options.

Some of the ingredients that we may use in our treatments, such as Tretinoin and hydroquinone, can increase your skin's sensitivity to sunlight. Therefore, we highly recommend daily use of a broad-spectrum sunscreen as part of your skincare routine.

Yes, the treatments we offer can also address other skin concerns, such as acne, scars and fine lines. Your doctor will work with you to address your skin's specific needs and goals.

We can treat hyperpigmentation on other areas of the body such as the trunk, back, arms or legs but depending on the size of the affected area this may incur a higher treatment fee since a larger volume of cream may be needed if the area is larger than the face and neck combined. Please note we do not treat sensitive areas such as the genitals or perineal region.

We can only offer treatments after a consultation with a doctor as they may use prescription medicines in the formula if they feel it is appropriate for you. This ensures that the treatment is safe for you to use and that it meets your treatment goals. Your doctor will also be able to answer any questions you have and provide you with a personalised treatment plan so you get the most out of your treatment and avoid irritation or side-effects.

Yes. We offer either online consultation forms or video appointments. Whatever option you choose, you will have the same doctor dedicated to you throughout your treatment and get a personalised experience.

You will have direct access to your doctor by email so you can ask questions, get advice and let them know if you have any problems.

No, you just need to reach out to your doctor by email and they will arrange your follow up. This maybe by email or a virtual video follow up depending on the problem.

Absolutely not. We never charge for any follow up or aftercare. You can contact your doctor at any time for advice, updates and any issues.

Nope! All our prices are as listed on the website. The fees also include delivery.

These will depend on the composition of your treatment and will be explained in more detail by your doctor. For example if a treatment contains Tretinoin and/or Hydroquinone these can cause some initial skin irritation including redness and peeling. This is usually temporary and subsides as your skin adjusts to the product. You may also experience purging. Always use sun protection especially while using Tretinoin and/or Hydroquinone, as they can increase your skin’s sensitivity to the sun and lead to rebound hyperpigmentation. For more info visit the individual ingredient pages.

We have different options in terms of the cream and use the one we feel is best for the patient's skin and the active ingredients we're using. Below are the ingredients for the main bases we use.

Light hydrating base: Purified water, cetearyl alcohol, glyceryl stearate, isohexadecane, isododeccane, stearyl behenate, cetyl alcohol, polyacrylate-13, polysorbate 60, PEG-75 stearate, polyisobutene, c13-c15 alkane, polyurethane-39, tocopheryl acetate, ascorbic acid, sodium bisulfite, benzoic acid (0.1%), sorbic acid (0.1%), polysorbate 20.

Emolliating (sensitive/dry skin) base: Aqua, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Cetearyl Alcohol, Sodium Stearoyl Lactylate, Propanediol, Undecane, Tridecane, HEA/Sodium Acryloyldimethyltaurate/Steareth-20 Methacrylate Copolymer, C13-14 Isoparaffin, Polysorbate 80, Decyl Glucoside, Glycerin, Palmitoyl Tripeptide-8, Propanediol, Rutin & Hydroxycinnamic Acid {from Cleome gynandra leaf extract}, Phenoxyethanol, Ethylhexylglycerin, Bisabolol, Edetate Disodium Dihydrate, Simethicone, Hyaluronic Acid Sodium Salt, Persea Gratissima Oil, Simmondsia Chinensis Seed Oil, Rosa Canina Flower Oil, Tocopheryl Acetate, Cocos Nucifera Oil, Lavandula Angustifolia Herb Oil, Melaleuca Alternifolia Leaf Oil, Rosemarinus Officinalis Leaf Oil, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride.

Compounded treatments like the ones we use are unlicensed medications because they are custom-made for each patient based on a specific formulation tailored to their unique needs. Unlike licensed medications, which are approved by regulatory bodies for general use, compounded treatments are created by pharmacists to meet the specific requirements of an individual patient as prescribed by their doctor. While they do not undergo the same approval process as licensed medications, they offer a personalised approach that can address specific concerns where a licensed treatment doesn't exist effectively under professional supervision.