Vitamin B3 (aka Niacinamide or Nicotinamide) is used in skincare to target large pores, uneven skin tone, dry skin and skin ageing.

Niacinamide, also known as Vitamin B3 or nicotinamide, is a water-soluble vitamin. It targets a variety of skin concerns. In the UK , you can get niacinamide in many skincare products but most common are gel, serum or cream formulas. We add niacinamide to some of our personalised prescriptions strength skincare treatments depending on the patient’s skin concerns or goals.

Benefits of Niacinamide

The main way niacinamide works through several mechanisms on the skin making it useful as a skincare serum or cream. It is an antioxidant that reinforces the skin’s barrier function. This helps skin to retain moisture and protect it from environmental stressors. It also plays a crucial role in cellular energy production and DNA repair helping repair skin and maintain its health. Additionally, Niacinamide boosts collagen levels which improves skin elasticity and can help to minimise the appearance of enlarged pores and wrinkles. Finally, niacinamide also possess anti-inflammatory properties which can help soothe irritated skin. As such, niacinamide is used in skincare for a number of benefits:

  • Calms Inflammation & Redness
  • Minimises Pores
  • Evens Out Skin Tone
  • Smoothes Texture
  • Boosts Hydration
  • Reduce Fine lines & Wrinkles
Fact sheet infographic on niacinamide benefits for skin in personalised prescription skincare cream in the UK

Treatments with Niacinamide

Niacinamide is a versatile skincare ingredient which can address a wide range of skin concerns. We add it to a number of our personalised skin treatment if we think it can provide benefit. These are the cream treatments we may add niacinamide to:

  • Acne Treatment
  • Hyperpigmentation or Melasma Treatments
  • Dark Spot Eraser
  • Skin ageing
  • Body….
  • Rosacea Treatment

Our Personalised Skincare Treatments

We offer custom made skincare treatments that may include niacinamide to treat a variety of skin concerns in the UK. Our doctors formulate every one of our personalised skincare treatments with precision to serve each patient’s skin concerns, goals and wishes. We will choose the ingredients at the optimal concentrations to address these needs. Hence, whether we add niacinamide to your skincare cream and what strength we use will depend on your specific skin concerns and other prescription ingredients we may use in your formula such as Tretinoin. Our doctors will work with you to prepare your treatment and monitor your progress to adjust your protocol as needed.



    Your doctor will design a personalised skincare treatment and program for you to follow. The cost of the consultation will be deducted from any skincare purchase.


    This is a 3 month supply of treatment. The cost depends on the type so please visit our treatment pages for full break down. Your doctor will create a personalised treatment taking into account your health, skin concerns, goals and wishes.

Treatment Time Clock

Treatment Time
15 Minutes

Duration of effect calendar

Duration of effect
3-4 Months

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Back to Work
Same Day

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Important Information

Niacinamide is generally well-tolerated and safe for all skin types that is widely available in skincare in the UK in a variety of preparations including serum, gel and cream products. Although it is well tolerated by most people, it’s important to start with a lower concentration if you have sensitive skin and gradually increase it to allow your skin to adjust. However, if you have persistent skin issues or if your condition does not improve with the use of niacinamide, get help from a medical professional. They can provide personalised advice and may recommend adjusting your skincare or trying a different formulation.


Niacinamide (in cream or other common formulations) is generally safe for most skin types, but there are some contraindications to be aware of. Individuals with known allergies to niacinamide or its components should avoid using products containing this ingredient. Additionally, while niacinamide is safe for use during pregnancy and breastfeeding, it’s always best to consult with a healthcare provider to ensure it’s appropriate for your specific situation.

Risks & Side Effects

Niacinamide is well-tolerated by most people, but some may experience mild side effects such as redness, itching, or slight irritation, especially when first introducing it into their skincare routine. Generally, these effects are typically temporary and can be managed by adjusting the frequency of use or the concentration of the product. However, if you experience severe reactions or allergies, discontinue use and get medical help.

Storage and Shelf Life

Store niacinamide products in a cool, dry place, away from direct sunlight and heat. Always check the expiration date on the product packaging and discard any product that has changed in colour, consistency, or smell.

Frequently asked questions

All our treatments are compound formulas made individually for each patient and should to be used over 3 months from when they're dispensed. Its important to use exactly as directed in your treatment plan.

This is a prescription only medicine and hence can only be offered if after a consultation your doctor feels it is safe and appropriate to include in your protocol. This ensures that the treatment they design is beneficial for you to use and will also ensure that it meets your treatment goals. Your doctor will also be able to answer any questions you have and provide you with a personalised treatment plan so you get the most out of your treatment and avoid irritation or side-effects.

You will have direct access to your doctor by email so you can ask questions, get advice and let them know if you have any problems.

No, you just need to reach out to your doctor by email and they will help you.

We do not charge for any follow up or aftercare. You can contact your doctor at any time for advice, updates and any issues.

No, you can just email your doctor and they will assist you.

No it is not. We are really passionate about putting you in control of your treatment. Everyone responds differently to their treatment so we don't think subscriptions make sense for a personalised journey. That's why we leave it up to you to let us know when you need a refill and we make it very easy to order these.

Yes. We provide two ways to access our doctors. You can either fill in an online consultation form or book an online video appointment. Please feel free to choose the option that is most convenient for you. Regardless of which consultation type you choose, you will have a single dedicated doctor throughout your treatment journey. They will create a personalised treatment protocol for your and provide ongoing aftercare and advice.

Unfortunately we can only offer our services to customers based in the UK.

Your product(s) will be delivered straight to your home. It usually takes 2-3 business days for products to arrive.

Nope! All our prices are as listed on the website. The fees also include delivery.


Compounded treatments like the ones we use are unlicensed medications because they are custom-made for each patient based on a specific formulation tailored to their unique needs. Unlike licensed medications, which are approved by regulatory bodies for general use, compounded treatments are created by pharmacists to meet the specific requirements of an individual patient as prescribed by their doctor. While they do not undergo the same approval process as licensed medications, they offer a personalised approach that can address specific concerns where a licensed treatment doesn't exist effectively under professional supervision.