Acne Treatment

Get Clear Skin with Personalised Topical Acne Skin Treatments

Most over-the-counter acne products and medical treatments take a one-size-fits-all approach. We don’t. After a consultation with a doctor, we design a topical gel or cream treatment using prescription-strength ingredients tailored to your skin, with medication included where appropriate. The treatment will target your specific acne pattern, skin sensitivity, scarring and hyperpigmentation risk, alongside any other skin concerns you also have. Your dedicated doctor will take care of you throughout your journey. They’ll also adjust each course of treatment based on how you respond. Best of all, you can access your acne treatment from the comfort of your home via our online skin clinic.

Consultation icon

Step 1
Choose a form or video consultation with your doctor

Treatment icon

Step 2
Personalised treatment plan with custom topical cream.

Monitoring icon

Step 3
Follow-up to refine protocol and reduce side effects.

Start Your Online Consultation

The journey to great skin starts here. Start your online consultation for personalised prescription-strength skincare.

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Understanding Acne

Acne develops when pores become blocked, oil production increases, bacteria build up and the skin’s immune response triggers inflammation. The result can range from blackheads and whiteheads to deeper, painful papules, pustules and nodules. It’s one of the most common skin conditions in the UK, and it doesn’t always clear up on its own, especially in adults. However, without proper treatment, acne can cause lasting acne scarring and post-inflammatory hyperpigmentation (dark marks that linger long after a breakout clears). Early, well-matched treatment reduces both active breakouts and the longer-term damage they leave behind.

Why Personalised Acne Treatment Works Better

First of all, acne isn’t one condition. It varies by type, severity, hormonal pattern and how your skin responds to treatment. So, someone with oily, resilient skin and deep inflammatory acne needs a very different formula from someone with sensitive, hyperpigmentation-prone skin and persistent comedones. A treatment that works brilliantly for one person can irritate or underperform for another. That’s why we tailor every prescription-strength treatment to you and review it at the end of each course. Your doctor can increase, reduce or swap ingredients based on what’s actually happening with your skin rather than continuing you on a rigid fixed protocol.

Personalised Prescription Strength Acne Treatment

We provide personalised topical adult acne treatment following an online consultation with a doctor. Your cream or gel formula is built around your acne type, medical history and treatment goals then refined at the end of each course.
We offer two types of custom protocol pathways depending on what your skin needs and preferences:

  • ACN: A single once a day acne treatment cream or gel. It is our standard acne treatment protocol for mild to moderate acne, or for maintaining results once acne is under control. ACN formulas can also address mild hyperpigmentation and uneven texture depending on the ingredients selected.
  • ACN+: A two-product protocol (morning and evening) for more persistent, severe, inflammatory, scarring or hyperpigmentation-prone acne. ACN+ provides more intensive coverage and is typically used for a defined period before stepping down to ACN for ongoing maintenance.

Acne Treatment Fees

  • VIRTUAL CONSULTATION£30

    Our expert doctor will design a personalised treatment for you and provide ongoing support. The cost of the consultation will be deducted from your first treatment.

  • ACN £90

    Standard acne treatment (30g) to treat breakouts, clear skin and tackle mild to moderate post inflammatory hyperpigmentation and scars. Usually lasts 3 months when used for face & neck.

  • ACN+ £150

    This is an advanced acne treatment to treat breakouts, clear skin and tackle severe post inflammatory hyperpigmentation and scars. It comes as two products (day and night treatment) each containing 30g treatment. It's typically used for no more than 6 months consecutively. Usually lasts 3 months when used for face & neck.

Treatment Time Clock

Treatment Time
15 Minutes

Duration of effect calendar

Duration of effect
3-4 Months

Back to work briefcase

Back to Work
Same Day

Ingredients Used in Our Acne Treatments

Every formula is customised. It can also be adjusted at the end of each 3-month course. We choose ingredients to target the specific drivers behind your breakouts, address other skin concerns and to protect against hyperpigmentation and scarring where needed. These are some of the active ingredients we may use in our topical acne treatment cream and gel formulas:

  • Tretinoin: A prescription retinoid that we may use either alone or with other ingredients in our acne cream or gel treatments. It works by promoting skin cell turnover to help unclog pores and reduce breakouts, smooth texture and fade mild hyperpigmentation. It needs careful monitoring as it is up to 20x more powerful than retinol.
  • Azelaic Acid: Has antibacterial, anti-inflammatory and keratolytic properties. It reduces acne-causing bacteria, decreases inflammation and promotes a smoother complexion. Particularly useful for patients prone to post-inflammatory hyperpigmentation as it can treat acne and hyperpigmentation at the same time with a lower irritation risk than many alternatives.
  • Niacinamide: Anti-inflammatory and sebum-regulating. It reduces redness, balances oil production and strengthens the skin barrier. Niacinamide also works well alongside stronger actives to help reduce irritation without adding harshness.
  • Clindamycin: A topical antibiotic that targets acne-causing bacteria and reduces inflammation and redness. We occasionally add this prescription medication to our acne creams for certain types of inflammatory breakouts in suitable patients for a limited period to avoid resistance.
  • Spironolactone: An anti-androgen ingredient that helps reduce oil production. We may add this prescription medication to your gel or cream for hormonal acne treatment for suitable patients, particularly where breakouts follow a cyclical pattern along the jawline, chin and lower face.
  • Arbutin: A natural skin-brightening agent that reduces melanin production. It helps treat post-inflammatory hyperpigmentation (PIH) from acne and lighten dark spots. However, arbutin is less suitable for patients with darker skin tones where dark marks are often the most persistent concern.
  • Hydroquinone: A prescription depigmenting ingredient that we may use for limited periods in suitable patients when hyperpigmentation is a dominant concern. It reduces pigmentation by inhibiting melanin production and is suitable for all skin tones.
  • Hydrocortisone: A corticosteroid that reduces inflammation and soothes irritated skin. We sometimes use it in the early stages to help skin adjust to active ingredients without excessive irritation.
Ingredient
Unblocks PoresAnti- inflammatoryReduces bacteriaControls oilFades HyperpigmentationSmooth TextureSkin Barrier
Tretinoin
Azelaic acid
Niacinamide
Clindamycin
Spironolactone
Arbutin
Hydroquinone
Hydrocortisone

All prescription ingredients are used in acne creams or gels only where we deem them safe, appropriate and suitable for you as an individual.

How Long Does Acne Treatment Take to Work?

Acne treatment is not a quick fix. That’s because it works by changing how your skin behaves over time rather than masking symptoms, and results vary between patients. So, some patients can begin to notice early improvement within 6 to 8 weeks with more meaningful progress typically developing over 3 to 6 months. However, rate of progress and amount varies from person to person depending on severity, skin type, response and consistency of use. Prescription-strength treatment can also help reduce the risk of longer-term damage to your skin.

In the first few weeks, acid or retinoid-based treatments can cause an adjustment phase. This may include some dryness, mild irritation or a temporary increase in breakouts (sometimes called purging). This is a recognised part of the process and one of the reasons we start with a strength and frequency suited to your skin rather than pushing maximum intensity from day one.

Why We Focus on Topical Acne Treatment

Topical treatment allows us to combine multiple active ingredients in a single formula, target them directly to the skin and adjust the balance at each review. For most patients with mild to moderate acne, a well-designed topical treatment can deliver strong results with lower systemic exposure and fewer side effects than oral medication. Our service is designed around topical prescription treatment. If your acne is severe or not responding adequately to topical therapy, your doctor will discuss this with you and may advise exploring other treatment options including systemic therapy.

Who is Suitable for Online Acne Treatment?

This service may be right for you if you:

  • Have mild to moderate acne that hasn’t responded well to over-the-counter products
  • Suffer from severe acne but have not tried topical treatments yet or wish to avoid systemic treatments for now
  • Have persistent adult acne, including hormonal or cyclical breakouts
  • Are concerned about post-inflammatory dark marks or early scarring
  • Need a structured treatment plan with ongoing doctor follow-up and not a one-off prescription
  • Prefer an online service with acne treatments delivered to your home

If your acne is severe, nodular or not responding to topical medication, your doctor may advise an alternative approach including alternative in-person or online services.

Start Your Online Consultation

The journey to great skin starts here. Start your online consultation for personalised prescription-strength skincare.

Start Consultation

Why Choose City Skin Clinic

We don’t believe in one-size-fits-all generic solutions. So, every treatment is prescribed by a doctor, tailored to your skin and adjusted at the end of each course based on how you respond. That means your treatment protocol evolves with you rather than staying the same. High standard of care and choice is what sets us apart from other online acne treatment services:

  • Doctor-led care from day one: Your journey starts with either a detailed form consultation or an in-depth video consultation with one of our doctors. The choice is entirely yours based on your availability and preferences. Your doctor will review your concerns, evaluate your skin and design a treatment plan that is unique to you.
  • Genuinely personalised: Treatment is designed around your acne type, skin sensitivity and scarring or hyperpigmentation risk. It can also be adjusted at the end of each cycle based on how your skin responds.
  • Ongoing follow-up: Your journey does not end after your consultation. You can directly contact your prescribing doctor at any point for further advice, progress review and refills.
  • Delivered to your door: Treatment shipped to your home with clear treatment plan. There is also unlimited aftercare.

From the initial consultation to follow-up, your doctor will provide expert advice, tailored treatments and unwavering support.

City Skin ClinicMost Online PlatformsIn-Person Clinics
ConsultationDoctor video or form consultationOnline form (clinician may vary)In-person appointment with doctor
TreatmentTopical personalised formulasFixed oral or topical treatments or custom with limited optionsFixed oral or topical treatments and/or in person treatments
AftercareDirect access to your doctorClinician team (may vary)Varies by provider
ConvenienceDelivered to your doorDelivered to your doorVaries by clinic

Frequently asked questions

No it is not. We are really passionate about putting you in control of your treatment. Everyone responds differently and we may adjust your treatment formula after completing each course based on how your skin responds. That's why we don't think subscriptions make sense for a personalised journey. We leave it up to you to let us know when you need a refill and we make it very easy to order these.

We encourage all our patients to express any preferences they have in terms of treatment during the consultation. Wherever possible we will respect and accommodate these as long as we feel it is medically safe and beneficial to do so. Ultimately our aim is to provide you with the best solution for your concern and we'll design your treatment to achieve that.

This depends on how frequently you use it and how much you use. In general if used as instructed then the treatment should last 3 months for use on the face and neck. Please note that compounded treatments always have an expiry date of 3 months.

Our treatments can be effective for various types of acne, from mild breakouts to cystic acne. However we recommend that if you have severe acne that you see a Dermatologist who can offer you more powerful treatments such as Roaccutane. During your consultation, the doctor will assess your skin to determine the most suitable treatment for you.

We can treat acne on other areas of the body such as the back, arms or legs but depending on the size of the affected area this may incur a higher treatment fee since a a larger volume of acne cream may be needed if the area is larger than the face and neck combined. Please note we do not treat sensitive areas such as the genitals or perineal region.

Results can vary from person to person. Some people may see improvements in as little as 6-8 weeks, while others may need several months of treatment. Patience and consistency are key.

Yes. Because every treatment is personalised, your doctor will take your skin sensitivity into account when selecting ingredients and strengths. If you have particularly sensitive or reactive skin, this will influence the formulation and the pace at which active ingredients are introduced. You can also discuss any sensitivities or concerns during your consultation.

Yes, we will create a treatment using actives that have been shown to reduce the appearance of acne scarring. However, the degree of improvement can vary depending on the type and severity of the scars. During your consultation, your doctor will assess your skin and devise a treatment plan best suited to address your specific concerns.

You do not need to bring a prescription. Your doctor will assess your skin and may include prescription ingredients such as tretinoin, clindamycin or hydroquinone in your treatment if they feel it would benefit you. These are prescribed as part of your consultation and included in the treatment we send you.

Acne can be a persistent condition, and while our treatments aim to control breakouts and reduce the appearance of acne, they do not cure it. Maintaining a consistent skincare routine and adopting a healthy lifestyle can help manage acne in the long term.

Yes, the treatments we offer can also address other skin concerns, such as uneven skin tone, sun damage, and fine lines. Our doctor will work with you to address your skin's specific needs and goals.

Yes. For acne with a hormonal pattern, typically along the jawline and chin, we can include ingredients that target hormonal drivers, such as topical spironolactone, alongside other actives.

We can only offer treatments after a consultation with a doctor as they may use prescription medicines in the formula if they feel it is appropriate for you. This ensures that the treatment is safe for you to use and that it meets your treatment goals. Your doctor will also be able to answer any questions you have and provide you with a personalised treatment plan so you get the most out of your treatment and avoid irritation or side-effects.

Yes. We offer either online consultation forms or video appointments. Whatever option you choose, you will have the same doctor dedicated to you throughout your treatment and get a personalised experience.

You will have direct access to your doctor by email so you can ask questions, get advice and let them know if you have any problems.

No, you just need to reach out to your doctor by email and they will arrange your follow up. This maybe by email or a virtual video follow up depending on the problem.

Absolutely not. We never charge for any follow up or aftercare. You can contact your doctor at any time for advice, updates and any issues.

Your doctor will advise on this at consultation. In general, we recommend simplifying your routine while using prescription actives to reduce the risk of irritation and interactions.

Nope! All our prices are as listed on the website. The fees also include delivery.

These will depend on the composition of your treatment and will be explained in more detail by your doctor. For example if a treatment contains Tretinoin and/or Hydroquinone these can cause some initial skin irritation including redness and peeling. This is usually temporary and subsides as your skin adjusts to the product. You may also experience purging. Always use sun protection especially while using Tretinoin and/or Hydroquinone, as they can increase your skin’s sensitivity to the sun and lead to rebound hyperpigmentation. For more info visit the individual ingredient pages.

Some patients experience a short adjustment phase usually in the first 2–6 weeks, including mild dryness, sensitivity or temporary breakouts. This is a normal response to many acne treatments and usually settles. Your doctor will help you manage this by starting at an appropriate strength and adjusting frequency or application if needed.

We have different options in terms of the cream and use the one we feel is best for the patient's skin and the active ingredients we're using. Below are the ingredients for the main bases we use.

Light hydrating: Purified water, cetearyl alcohol, glyceryl stearate, isohexadecane, isododeccane, stearyl behenate, cetyl alcohol, polyacrylate-13, polysorbate 60, PEG-75 stearate, polyisobutene, c13-c15 alkane, polyurethane-39, tocopheryl acetate, ascorbic acid, sodium bisulfite, benzoic acid (0.1%), sorbic acid (0.1%), polysorbate 20.

Emolliating (sensitive/dry skin): Aqua, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Cetearyl Alcohol, Sodium Stearoyl Lactylate, Propanediol, Undecane, Tridecane, HEA/Sodium Acryloyldimethyltaurate/Steareth-20 Methacrylate Copolymer, C13-14 Isoparaffin, Polysorbate 80, Decyl Glucoside, Glycerin, Palmitoyl Tripeptide-8, Propanediol, Rutin & Hydroxycinnamic Acid {from Cleome gynandra leaf extract}, Phenoxyethanol, Ethylhexylglycerin, Bisabolol, Edetate Disodium Dihydrate, Simethicone, Hyaluronic Acid Sodium Salt, Persea Gratissima Oil, Simmondsia Chinensis Seed Oil, Rosa Canina Flower Oil, Tocopheryl Acetate, Cocos Nucifera Oil, Lavandula Angustifolia Herb Oil, Melaleuca Alternifolia Leaf Oil, Rosemarinus Officinalis Leaf Oil, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride.

Compounded treatments like the ones we use are unlicensed medications because they are custom-made for each patient based on a specific formulation tailored to their unique needs. Unlike licensed medications, which are approved by regulatory bodies for general use, compounded treatments are created by pharmacists to meet the specific requirements of an individual patient as prescribed by their doctor. While they do not undergo the same approval process as licensed medications, they offer a personalised approach that can address specific concerns where a licensed treatment doesn't exist effectively under professional supervision.

Those services typically use a fixed monthly subscription model, offer only form consultations and have monitoring by a care team. We provide individually designed formulas, choice of online or form consultation and care by the same doctor throughout your journey. Our treatments are highly customisable and with the ability to further adjust ingredients, strengths and combinations at each new course based on your response.

If your acne isn't responding adequately after a reasonable period, your doctor will discuss next steps. This may include modifying future formulas, adjusting protocols or recommending other services for systemic treatment.

No, you can just email your doctor and they will assist you.