Metronidazole
Metronidazole is used in prescription rosacea treatments
Metronidazole is a highly effective topical antibiotic commonly used in prescription creams and gels for treatment of rosacea. Its powerful anti-inflammatory and antimicrobial properties can help significantly reduce redness, acne and irritation associated with rosacea. In the UK, metronidazole is available by prescription by itself or part of compounded creams and gels to treat certain types of rosacea.
Benefits in Skincare
Rosacea is a chronic skin condition which can cause redness, visible blood vessels, and in some cases even pustules or bumps. Whilst this is a condition without a cure, there are a few topical treatments that can help address the symptoms of rosacea. Metronidazole cream is one such rosacea treatment which works by reducing inflammation and suppressing bacteria associated with flare-ups. Metronidazole is particularly effective in managing papulopustular rosacea by helping clear pimples and pustules. When used correctly and appropriately, the main benefits of using metronidazole cream for Rosacea include:
- Anti-inflammatory action: Reduces facial redness, swelling and irritation.
- Antimicrobial properties: Targets specific bacteria that can trigger rosacea flare-ups.
- Improved skin texture: Helps smooth out uneven skin and minimise breakouts.
- Gentle formula: Suitable for sensitive skin.

Treatments with Metronidazole
Metronidazole cream can be used by itself to manage certain types of rosacea. It can also be safely compounded with other ingredients like azelaic acid, ivermectin and niacinamide for a more comprehensive rosacea treatment. Where appropriate, we may sometimes also metronidazole it with multi-use compounds like tretinoin to target additional skin conditions such as:
Personalised Prescription Metronidazole Creams Online in the UK
In the UK, medications containing metronidazole cream and gel are available by prescription only for rosacea. Our doctors use metronidazole in our personalised rosacea treatments if they think that it is appropriate and safe for the patient. For your bespoke skin treatment, you will need to complete an online consultation form or book a virtual video consultation with one of our doctors first. They will include metronidazole and/or other ingredients in your rosacea treatment if they think it is right for your skin. They’ll of course take into account any wishes or preferences you’ve expressed where possible. Your doctor will also provide you with a customised protocol and ongoing follow up throughout your treatment. You will have access to your doctor by email at any time as part of your treatment.
PERSONALISED TREATMENT FEES
VIRTUAL CONSULTATION£30
Your doctor will design a personalised skincare treatment and program for you to follow. The cost of the consultation will be deducted from any skincare purchase.
PERSONALISED SKIN TREATMENT£90-150
This is a 3 month supply of a bespoke skin treatment. The cost depends on whether you will require a once daily or twice daily treatment so please visit our treatment pages for full break down. Your doctor will create a personalised treatment taking into account your health, skin concerns, goals and wishes.
Treatment Time
15 Minutes
Duration of effect
3-4 Months
Back to Work
Same Day
What’s the Difference Between Compound Metronidazole vs Generic Creams & Gels?
In the UK, topical metronidazole cream or gel is available only through prescription for rosacea and other skin conditions. This is usually as an off-the-shelf licensed topical cream or gel. Compounded treatments containing metronidazole can also be prescribed. These are custom-made by specialist pharmacies based on individual prescriptions. The active ingredient in compounded metronidazole preparations is the same as in the generic creams and gels. Compounded treatments however offer flexibility as they allow the addition of other ingredients to target rosacea or other skin concerns in a single product. Since compounded treatments are freshly made for each patient, they tend to have shorter expiration dates (usually up to 3 months). Licensed off-the-shelf products like usually have longer shelf lives before opening.

Important Information
Topical metronidazole is a prescription only antibiotic treatment available in cream or gel forms in the UK used to treat skin conditions like infections and certain types of rosacea. Its use in rosacea is mainly due to its strong anti-inflammatory and antimicrobial properties. With correct use, it can help alleviate symptoms but there are important considerations.
Contraindications
Do not use topical metronidazole cream or gel products if you are allergic to metronidazole or any other ingredients in the formulation. There is currently not enough data on safety and efficacy for rosacea patients younger than 18 years of age. Use during pregnancy or breastfeeding should only occur with explicit medical advice. Inform your healthcare provider if you have any underlying skin conditions, allergies or are planning to conceive in the near future before starting treatment.
How to use Topical Metronidazole
Use metronidazole exactly as prescribed by your doctor or healthcare provider. Typically, most protocols advise applying a thin layer evenly on clean, dry skin once or twice daily. Avoid applying metronidazole to broken skin, open wounds or severely irritated areas. Keep metronidazole cream away from your eyes, mouth and other mucous membranes. Always follow your doctor’s specific instructions including dose, frequency and application methods.
Side Effects of Metronidazole
Common side effects of metronidazole cream or gel for rosacea include temporary irritation, redness, dryness or flaking. These are most likely to occur during initial use and typically subside with continued use. Rarely, more severe irritation or allergic reactions like itching, swelling or significant redness might occur. If you experience any sort of side effect, seek medical advice immediately.