POSTED: 30 Apr 2024

Do Oestrogen Face Creams Really Work?

Sometimes it feels like the beauty industry throws a new product at us every day. Each one promises to reverse the signs of ageing and deliver younger, more radiant skin. Disappointingly, a lot of these turn out to be over-hyped, subtle variations on existing staples. It is rare to find something genuinely new, let alone one that lives up to the promise. Many now bill oestrogen face creams as a game-changer in anti-ageing skincare in the USA. It is only a matter of time before they make waves in the UK. In this article we take a deep dive into how and whether oestrogen creams for the face work. We also explore their benefits, side effects and best use, all with the caution a hormonal product deserves.

What is Oestrogen Cream?

These are creams you apply to the skin that contain a natural hormone called oestrogen (also spelled estrogen). Oestrogen plays a crucial role in the reproductive system and secondary sexual characteristics. Cosmetic oestrogen creams use the hormone’s properties to refresh skin by promoting hydration, elasticity and smoothness. They aim to enhance elasticity and improve moisture retention, and they may reduce the appearance of fine lines and wrinkles by stimulating collagen production. In countries where they are available, people mainly use them for anti-ageing skincare. They may also help reverse some effects of ageing and environmental damage for a plumper, more youthful complexion. They are particularly useful for those experiencing hormonal changes, such as post-menopausal women, who often notice benefits in skin texture and firmness.

What’s the Difference Between Oestrogen Face Creams and HRT?

Oestrogen face creams and hormone replacement therapy (HRT) serve very different functions. Oestrogen face creams are topical treatments for local application on the skin. They primarily address signs of ageing such as dryness, thinning skin and wrinkles. They do this by increasing collagen, improving elasticity and boosting hydration locally, without significantly affecting oestrogen levels elsewhere in the body.

HRT (or BHRT), on the other hand, is a systemic treatment, typically given orally, transdermally via patches or vaginally. Its purpose is to replace the oestrogen that the body no longer produces in sufficient amounts after menopause. As a result, HRT can ease a wide range of menopausal symptoms, including hot flushes, night sweats, mood changes and bone density loss. Its systemic nature also carries very different risks and benefits compared with the limited, local application of an oestrogen face cream.

How Do Oestrogen Skin Creams Work?

Oestrogen cream works by delivering oestrogen directly to the skin, where it can help maintain a youthful, healthy complexion. Once applied, the oestrogen penetrates the skin and binds to specific receptors on skin cells. This hormonal interaction activates genes that boost the production of collagen, an essential protein for elasticity and strength. Collagen helps maintain firmness and structure, which reduces the appearance of sagging and wrinkles. Oestrogen also increases the skin’s ability to retain water. This boosts hydration and makes the skin look plumper and more radiant. On top of this, it supports skin renewal and repair. This can give a more even tone, reduce age spots and speed up wound healing.

How Did Oestrogen Enter Skincare?

The idea of using hormones in skincare dates back to the early 20th century. That was when researchers first began to understand the role hormones play in skin health and ageing. By the mid-20th century, as synthetic hormones became more accessible, companies started adding oestrogen to creams and lotions. These were mainly aimed at menopausal women and the dryness, thinning and wrinkles of ageing skin.

In the latter half of the century, hormone-infused products, including oestrogen face creams, began to face enormous scrutiny. Concerns over the potential systemic effects of topical hormones led to stricter regulations. Agencies in Europe and the United States required better safety testing and clearer labelling. This caused a temporary decline in their popularity. Despite that, there has been a resurgence in recent years, for a few main reasons:

  • Technological advances: Microencapsulation and better emulsifiers have improved how active ingredients reach the skin, which helps keep topically applied oestrogen localised and reduces systemic absorption.
  • Increased research: We now understand more about how hormones affect the skin, with evidence that topical oestrogen can improve elasticity and moisture without the risks of systemic HRT.
  • An ageing population: Globally, this has increased demand for anti-ageing products that are both effective and safe.
  • Holistic beauty trends: These have championed oestrogen as a naturally occurring hormone.
  • Clever marketing: Campaigns have tapped into themes of empowerment and self-care, so these products now target not only menopausal women but also younger consumers as prevention.

What are the Benefits of Oestrogen Face Cream?

The main attraction of oestrogen face creams is their effect on skin regeneration. They address the aesthetic concerns of ageing whilst also playing a more therapeutic role in overall skin health. The key benefits include:

  • Skin elasticity and firmness: Oestrogen helps maintain strength and elasticity by stimulating collagen production. Regular use can help combat sagging, shrink pores and reduce fine lines and wrinkles.
  • Skin hydration: Oestrogen increases the skin’s ability to retain moisture, which leads to better hydration. Well-hydrated skin looks plumper, smoother and more radiant.
  • Fewer wrinkles: By boosting collagen and hydration, an oestrogen face cream can diminish existing wrinkles. It can also slow the development of new ones, especially around the eyes and mouth.
  • Even skin tone: Oestrogen can help regulate melanin production, which reduces the likelihood of age spots and hyperpigmentation for a more even complexion.
  • Skin repair and renewal: Oestrogen can enhance the skin’s natural repair processes and support the renewal of skin cells, which helps heal damage more quickly. This matters for skin exposed to environmental stressors like UV rays and pollution.
  • Calmer skin: An oestrogen face cream can have a soothing effect, reducing redness and calming irritation, which makes it useful for sensitive or reactive skin.

What are the Side Effects and Risks?

Although oestrogen creams can offer significant benefits, they also carry potential side effects and risks. Commonly reported effects include mild skin irritation, redness and sensitivity at the application site. Adjusting the strength, formulation or how often you apply it is often enough to manage these, under the guidance of the prescriber. More concerning is the potential for systemic absorption, which means oestrogen reaches the bloodstream. Modern formulations typically minimise this risk, but it remains a possibility. If it happens, you may experience hormonal effects such as changes in menstrual patterns or mood. Most importantly, in people with hormone-sensitive conditions, such as certain cancers, oestrogen cream could potentially make the condition worse. For this reason, as with any product containing active hormones, it is vital to consult a healthcare professional before starting use.

Who Should Use Oestrogen Face Creams?

Oestrogen face creams have a range of benefits that can give more youthful, radiant skin. However, they are not suitable for everyone, and you should only use them when appropriate to get the most from the treatment and reduce risks. The most suitable candidates are:

  • Post-menopausal women: These are the most common and most suitable users. Menopause leads to a drop in oestrogen, which can cause dryness, loss of elasticity and the appearance of fine lines and wrinkles, all of which an oestrogen face cream may help address.
  • Anyone with ageing skin: This includes men and pre-menopausal women, since natural oestrogen levels decline with age in everyone. These creams may reduce visible signs of ageing, minimise pores and firm the skin by boosting collagen.
  • Those with thin or fragile skin: Topical oestrogen can increase skin thickness and durability, which enhances resilience and reduces susceptibility to damage.

Who Should Avoid Oestrogen Face Creams?

Like anything, oestrogen skin creams are not for everybody, and used inappropriately they can increase the risk of side effects. People who should not use them include:

  • Those with hormone-sensitive conditions: Anyone with hormone-sensitive cancers (such as breast, ovarian, bowel or prostate) should avoid oestrogen face creams, since oestrogen can potentially stimulate the growth of hormone-sensitive cells. It is crucial for anyone with these conditions, a past history of them or a family history to consult their healthcare provider first.
  • Pregnant or nursing women: Avoid these, as there is no robust data on the safety of topical oestrogen during pregnancy or breastfeeding. It is also wise to avoid them if you are planning or actively trying to conceive.
  • People with severe acne or rosacea: Hormone products can influence sebum production and skin cell turnover, which may worsen these conditions, so caution is needed before starting.

Where Can You Get Oestrogen Face Creams?

This is where things get interesting. Access to oestrogen face creams varies enormously around the world, depending on each country’s regulations, healthcare systems and market preferences.

The use of hormones like oestrogen in skincare is a rapidly evolving field, driven by consumer demand and improving technology. It is likely to grow over the next few years as research continues and regulation improves to ensure safety, and the next generation of oestrogen-based skincare will probably tap into precision-medicine trends with more targeted treatments. That said, these products blur the line between skincare and medicine. It is crucial to understand that, like tretinoin or Botox, the end goal may be cosmetic, but you should still approach an oestrogen face cream with caution and under medical guidance. Anyone considering one should consult a healthcare professional to make sure it is appropriate and safe for them.

Please note, we do not provide oestrogen creams at City Skin Clinic. Our online skin clinic offers safe and effective custom skincare treatments. Where appropriate our doctors use ingredients such as tretinoin and hydroquinone to treat skin conditions like acne, hyperpigmentation, melasma and skin ageing. To start your personalised skincare plan, book a virtual video consultation or use our online consultation form. The journey towards great skin starts here.

This article is intended for general informational purposes only and is not a substitute for medical advice, diagnosis or treatment. Always consult a qualified medical provider for any medical concerns or questions you might have.

Authored by:

Dr Amel Ibrahim
Aesthetic Doctor & Medical Director
BSC (HONS) MBBS MRCS PHD
Founder City Skin Clinic
Member of the Royal College of Surgeons of England
Associate Member of British Association of Body Sculpting GMC Registered - 7049611

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