This is a melanin suppressing compound targets hyperpigmentation and uneven skin tone.

Arbutin is a naturally occurring compound found in various plants such as bearberry, blueberry and cranberry. It suppresses excess pigment production. For this reason arbutin is used to treat hyperpigmentation on the skin and even out c. Arbutin is a gentle alternative to hydroquinone and is often used in skincare in cream or serum forms.

Benefits in Skincare

The main way that arbutin works is by inhibiting tyrosinase which is an enzyme crucial in the production of melanin. By blocking this enzyme, arbutin reduces melanin production, hence it is mainly used to treat hyperpigmentation on the skin and brighten the complexion. Additionally, arbutin is an antioxidant so it can help protect the skin from environmental stressors, premature ageing and free radical damage. Arbutin is popular in both over-the-counter and prescription-strength skincare as a serum or cream on the following skin concerns:

  • Hyperpigmentation & Melasma
  • Dark Spots & Uneven Skin Tone
  • Sun Damage & Age Spots
  • Skin Ageing
Infographic for arbutin effect on skin in personalised prescription skincare

Treatments with Arbutin

We create each and every one of our personalised skin treatments according to the patient’s skin concerns, goals, and wishes. Arbutin is a useful ingredient which we may use if we think it is beneficial to the following personalised skincare cream treatments:

  • Acne
  • Hyperpigmentation
  • Melasma
  • Body hyperpigmentation or acne
  • Dark Spot Fader
  • Glow Glass Skin

Arbutin Cream Treatment in the UK

In the UK, arbutin is widely available in over-the-counter topical products (mainly gel, serum, and cream) and prescription formulations. We sometimes add arbutin to our personalised cream treatments if we think it is appropriate and safe for the patient. We may use it as part of an active treatment, for protocols where patients need to take a break from Hydroquinone or in maintenance treatments. The strength of arbutin and other ingredients in the formula that we add to the cream depends on the patient’s needs, goals and wishes.

To access our personalised skincare treatments, you will need to complete the online consultation form or book a virtual video consultation with one of our doctors first. They will design a treatment plan that they think will best serve your needs and will take into account any wishes or preferences you’ve expressed as much as possible. Your doctor will provide you with a skincare routine to follow and ongoing monitoring throughout your journey. You will be able to contact your doctor by email at any time as part of your treatment.



    Your doctor will design a personalised skincare treatment and program for you to follow. The cost of the consultation will be deducted from any skincare purchase.


    This is a 3 month supply of treatment. The cost depends on the type so please visit our treatment pages for full break down. Your doctor will create a personalised treatment taking into account your health, skin concerns, goals and wishes.

Treatment Time Clock

Treatment Time
15 Minutes

Duration of effect calendar

Duration of effect
3-4 Months

Back to work briefcase

Back to Work
Same Day

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Important Information

Arbutin is suitable for a wide range of skin types and conditions and available in many serum or cream product in the UK. Although this is a popular skincare ingredient, you should be aware of potential risks, side effects and contraindications.

Combining Arbutin with Other Ingredients

Arbutin can be safely combined with several other skincare ingredients to enhance its effects. However, it’s important to take care whilst using arbutin with strong exfoliants or irritants such as retinoids and seek the help of a doctor especially if you have sensitive skin.


People with known allergies to arbutin or its plant sources should avoid using arbutin-containing products. As with any skincare ingredient, it is best to consult with a healthcare provider if you are pregnant, breastfeeding or have any underlying skin conditions to ensure it is safe for you to use.

Safety and Side Effects

Arbutin is typically well-tolerated, but some people may experience mild side effects such as redness, itching, or irritation. This is especially likely if used in high concentrations. These effects are usually temporary and can be managed by adjusting the frequency of use or the concentration. If you experience severe reactions or allergies, discontinue use and seek medical help.

Storage and Shelf Life

Store arbutin skincare products in a cool, dry place, away from direct sunlight and heat. Always check the expiration date on the product packaging and discard any product that has changed in colour, consistency, or smell.

Frequently asked questions

All our treatments are compound formulas made individually for each patient and should to be used over 3 months from when they're dispensed. Its important to use exactly as directed in your treatment plan.

This is a prescription only medicine and hence can only be offered if after a consultation your doctor feels it is safe and appropriate to include in your protocol. This ensures that the treatment they design is beneficial for you to use and will also ensure that it meets your treatment goals. Your doctor will also be able to answer any questions you have and provide you with a personalised treatment plan so you get the most out of your treatment and avoid irritation or side-effects.

You will have direct access to your doctor by email so you can ask questions, get advice and let them know if you have any problems.

No, you just need to reach out to your doctor by email and they will help you.

We do not charge for any follow up or aftercare. You can contact your doctor at any time for advice, updates and any issues.

No, you can just email your doctor and they will assist you.

No it is not. We are really passionate about putting you in control of your treatment. Everyone responds differently to their treatment so we don't think subscriptions make sense for a personalised journey. That's why we leave it up to you to let us know when you need a refill and we make it very easy to order these.

Yes. We provide two ways to access our doctors. You can either fill in an online consultation form or book an online video appointment. Please feel free to choose the option that is most convenient for you. Regardless of which consultation type you choose, you will have a single dedicated doctor throughout your treatment journey. They will create a personalised treatment protocol for your and provide ongoing aftercare and advice.

Unfortunately we can only offer our services to customers based in the UK.

Your product(s) will be delivered straight to your home. It usually takes 2-3 business days for products to arrive.

Nope! All our prices are as listed on the website. The fees also include delivery.


Compounded treatments like the ones we use are unlicensed medications because they are custom-made for each patient based on a specific formulation tailored to their unique needs. Unlike licensed medications, which are approved by regulatory bodies for general use, compounded treatments are created by pharmacists to meet the specific requirements of an individual patient as prescribed by their doctor. While they do not undergo the same approval process as licensed medications, they offer a personalised approach that can address specific concerns where a licensed treatment doesn't exist effectively under professional supervision.