Melatonin

Naturally produced by the body, melatonin’s main function is to regulate sleep cycles. However, it also plays a role in protecting the hair follicle and stimulating growth. In its topical form, melatonin can directly act on the scalp neutralising free radicals and prolongs the hair growth cycle. It also reduces inflammation and may even delay greying. As such, topical melatonin is increasingly available in hair loss and beard growth treatments in the UK.

Benefits in Hair Loss

There is growing scientific evidence to suggest that melatonin can act as an effective anti-hair loss ingredient by influencing several key biological mechanisms. Chief amongst these is melatonin’s ability to prolong the anagen (active growth) phase of the hair cycle. Melatonin is also a powerful antioxidant which helps to reduce oxidative stress. This can protect follicles from premature damage and support its natural regeneration process. There is even some evidence to suggests that melatonin may help regulate circadian rhythms within the hair follicle cells themselves which further enhances their growth potential and metabolic function. As such, the main benefits of using topical melatonin in hair growth treatments include:

• Stimulates Hair Growth
• Slows Androgenetic Hair Loss
• Improves Hair Density
• Protects Follicles from Oxidative Stress
• Can Be Combined with Other Ingredients to Enhance Their Effects

Treatments with Topical Melatonin

At City Skin Clinic, we use topical melatonin in our personalised hair loss and beard growth treatments where appropriate depending on the patient’s needs. We may add melatonin to the following custom formulations to help regrow hair:

• Hair Loss Treatments for Men
• Hair Loss Treatments for Women
• Beard Growth Treatments

Complimentary Actives

Generally, we tend to combine topical melatonin with other hair growth ingredients to boost their combined efforts. The composition of your formula depends on your type of hair loss and individual patient circumstances. The most common ingredients we use alongside melatonin include:

• Tretinoin: enhance the absorption of hair growth ingredients in to the scalp.
• Minoxidil: stimulates hair regrowth and increases density.
• Spironolactone: helps reduce androgen effects on follicles to treat hair loss in some cases of pattern hair loss.
• Hydrocortisone: reduces scalp irritation.
• Finasteride: reduces hair loss and promote regrowth by inhibiting the actions of DHT on follicles.
• Dutasteride: inhibits harmful DHT effects on follicles to enhance hair regrowth.
• Biotin: can strengthen hair by supporting keratin production.
• Caffeine: stimulates hair growth, reduces shedding and increases blood supply to the scalp.

Topical Melatonin Hair Loss Treatments in the UK

In the UK, melatonin in all its forms (including topical) is a prescription only medicine. For hair growth, it can be included in compounded prescription serums and creams for appropriate patients. Melatonin may be paired with other hair growth ingredients like Minoxidil, Finasteride, Caffeine or Spironolactone depending on the clinical need.

At City Skin Clinic, we create personalised hair loss and beard growth serums that may include melatonin where appropriate. Every formulation is tailored to the patient’s specific hair loss, medical history and treatment goals. Our doctors aim to create custom formulas which can maximise results whilst minimising side effects. To access our custom hair loss and beard treatments, you’ll first need to complete an online consultation form or book a virtual video consultation with one of our doctors. They will analyse your needs and design the most suitable and safe treatment plan for you. Your preferences and concerns will always be taken into account where possible, and you’ll receive ongoing support and monitoring throughout your treatment journey. You can also contact your doctor by email at any time throughout your treatment for personalised guidance.

Important Information

Topical melatonin is usually a safe and well-tolerated ingredient in hair loss treatments when used as directed. However, it’s still important to be aware of potential side effects and considerations including that topical melatonin is a prescription only treatment in the UK even for uses like hair loss.

Safety and Side Effects

Most people tolerate topical melatonin well especially at the concentrations commonly used in compounded hair loss treatments. That said, some people may experience mild scalp irritation, redness, itching or dryness especially when starting treatment. These symptoms are typically short-lived and often resolve with continued use or minor adjustments in formulation. If you develop more severe irritation or signs of an allergic reaction (e.g. rash, swelling or persistent pain) you must stop using the product immediately and seek medical advice.

Contraindications

Although topical melatonin is generally safe, there are certain circumstances in which you should exercise caution or get medical supervision. These include:

• Scalp Conditions: If you have existing scalp disease such as eczema, psoriasis, fungal infections or open wounds, speak with your healthcare provider before using topical melatonin. This is because it may worsen your condition or delay healing.
• Pregnancy and Breastfeeding: The safety of topical melatonin during pregnancy or breastfeeding has not been conclusively studied. As a precaution, always consult with your doctor before use in these situations.
• Allergies: Avoid melatonin-based treatments if you have a known allergy to melatonin or any other ingredients in the formula. Always check the full ingredient list before starting a new topical product.

Storage and Shelf Life

Store your melatonin-containing hair care products in a cool dry place away from direct sunlight and heat. Always check the pharmacy labels for shelf life and expiry dates.